Anti-BCL2 Antibody

This rabbit polyclonal antibody from Antibodies.com recognizes human BCL2, a 26 kDa anti-apoptotic regulator of the BCL-2 protein family that governs mitochondrial outer membrane permeabilization and programmed cell death. Raised in rabbit and supplied as an unconjugated 100 µl preparation, the reagent is validated for Western Blot (WB) and Immunofluorescence (IF) workflows in human cells and tissue sections.

Because BCL2 sustains lymphocyte survival and is characteristically overexpressed in follicular lymphoma, this primary antibody is routinely used to profile apoptosis pathways in lymphoma cell lines such as SU-DHL-4 and Raji, to monitor BCL2 induction under chemotherapeutic challenge, and to study mechanisms of venetoclax response and resistance. The polyclonal format recognizes multiple epitopes on the BCL2 target, supporting consistent detection across denaturing immunoblot conditions. Store refrigerated at 4°C to preserve activity across repeated Western Blot and immunofluorescence experiments.