Anti-BCL2 Antibody

This rabbit polyclonal antibody targets BCL2 (B-cell lymphoma 2), an anti-apoptotic mitochondrial membrane protein studied extensively in apoptosis and oncology research. Raised in rabbit and supplied as an unconjugated polyclonal reagent in a 100 µl volume, it is validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples and tissue sections.

BCL2 controls programmed cell death by blocking cytochrome c release from the outer mitochondrial membrane and is most often investigated in follicular lymphoma, chronic lymphocytic leukemia, and other hematological cancers where the t(14;18) translocation drives overexpression. Researchers use this reagent to confirm BCL2 expression patterns in tumor biopsies, assess treatment response in cell culture and other in vitro models, and probe subcellular mitochondrial localization by immunofluorescence in fixed cells.

Storage and handling: aliquot the vial upon receipt and store frozen at -20 °C, protected from light. Avoid repeated freeze-thaw cycles to preserve antibody performance. Short-term working aliquots may be refrigerated at 4 °C with an appropriate antimicrobial preservative. This product from Antibodies.com is intended for research use only and is not cleared for diagnostic or therapeutic applications.