Anti-Bcl-XL (phospho Thr115) Antibody

Produced in rabbit hosts as an unconjugated polyclonal IgG reagent, this Antibodies.com primary antibody specifically recognises Bcl-XL when phosphorylated at threonine 115 (Thr115). The lyophilised 100 µg vial format allows flexible reconstitution in buffer of choice for downstream assays.

Bcl-XL is an anti-apoptotic member of the Bcl-2 family, and phosphorylation at Thr115 has been linked to JNK-mediated signalling during the cellular DNA damage response, modulating the protein's ability to suppress apoptosis. Investigators studying programmed cell death, oncogenic transformation, and chemoresistance pathways use this reagent to probe site-specific phosphorylation events in human cell lysates and tissue preparations.

The antibody has been validated for ELISA-based detection of phospho-Bcl-XL (Thr115) and reacts with human samples. For short-term use, reconstituted aliquots should be refrigerated; the lyophilised powder is stable at 4°C and can be aliquoted to limit freeze-thaw cycles of the working stock.