Anti-Bcl-2 Antibody

Bcl-2 is a 26 kDa integral membrane protein anchored to the outer mitochondrial membrane, where it suppresses apoptosis by blocking cytochrome c release and caspase activation. This unconjugated rabbit polyclonal reagent from Antibodies.com targets the human Bcl-2 protein and cross-reacts with monkey samples, making it useful for apoptosis and oncology research. Validated for Western blot, immunohistochemistry, and ELISA workflows, the antibody is supplied as 50 µl of liquid stock. Researchers commonly apply it to study follicular lymphoma t(14;18) translocations, chemoresistance mechanisms, and mitochondrial survival pathways in cancer cell lines and primary tissue sections.