Anti-Bcl-2 Antibody

The Bcl-2 target is the founding member of the Bcl-2 family of apoptosis regulators, an anti-apoptotic protein located on the outer mitochondrial membrane that controls programmed cell death. This unconjugated rabbit polyclonal reagent from Antibodies.com is supplied as 100 µl and is validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows. It detects the human, mouse, and rat Bcl-2 protein, supporting research into programmed cell death, mitochondrial permeabilization, and oncology models including follicular lymphoma and leukemia. The polyclonal format increases the chance of binding multiple epitopes, which can be useful when working with post-translationally modified samples or tissues showing variable expression. Researchers commonly apply this reagent to lymphoma and leukemia cell lines, formalin-fixed paraffin-embedded sections, and apoptosis-induction assays. Storage at -20°C in working aliquots helps preserve activity across freeze-thaw cycles.