Anti-BCL-2 (Ab-56) Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com recognizes BCL-2, the founding member of the BCL-2 family of apoptosis regulators that governs mitochondrial outer-membrane permeabilization and is best known for blocking programmed cell death. The target is studied intensively in follicular lymphoma, chronic lymphocytic leukemia, breast carcinoma, and other solid tumor research programs where BCL-2 overexpression drives tumor cell survival. Supplied as 100 µl in a single vial, the antibody is validated for Western blot analysis, immunohistochemistry on paraffin-embedded tissue sections, and immunofluorescence staining of cultured human cells. Because the reagent is unconjugated, it can be paired with a secondary detection chemistry of the researcher's choice, and the polyclonal population should be aliquoted upon arrival and stored refrigerated in working aliquots to limit freeze-thaw damage of the active fraction. Reactive against human BCL-2, the product is intended for research use only and supports apoptosis, oncogene signaling, and cancer biology investigations in cell biology and pathology laboratories.