Anti-BCHE Antibody

The BCHE gene encodes butyrylcholinesterase, a serine hydrolase closely related to acetylcholinesterase that hydrolyzes choline-based esters, including acetylcholine and a range of ester-containing drugs and toxins. Antibodies.com provides this rabbit polyclonal reagent for researchers investigating BCHE expression, cholinergic signaling, and hepatic detoxification pathways.

This unconjugated antibody is validated for Western blot (WB) and immunofluorescence (IF) workflows and recognizes the BCHE target in Human, Mouse, and Rat samples. The polyclonal antibody pool offers broader epitope coverage than monoclonal alternatives, supporting detection of full-length and variant isoforms of the enzyme across tissue lysates and cultured cells.

Supplied as a 100 µl liquid aliquot, the reagent integrates readily into standard immunolabeling pipelines. Pair with HRP- or fluorophore-conjugated secondary antibodies for chemiluminescent western blot imaging or fluorescence microscopy. Typical research contexts include neuroscience, toxicology, and hepatology, where butyrylcholinesterase levels serve as indicators of organophosphate exposure, liver function, and certain neurodegenerative conditions.