Anti-BCAM Antibody

This rabbit polyclonal primary antibody targets the basal cell adhesion molecule (BCAM), a heavily glycosylated single-pass transmembrane glycoprotein of the immunoglobulin superfamily that serves as a receptor for laminin alpha-5 and contributes to cell-matrix adhesion, erythrocyte signaling, and vascular remodeling. Supplied by Antibodies.com as an unconjugated reagent at 100 uL per vial, the antibody is validated for western blot and immunohistochemistry on human and mouse specimens, supporting studies of Lutheran blood group biology, sickle cell vaso-occlusion, epithelial differentiation, and tumor cell adhesion.

Generated in rabbit hosts and affinity-purified for batch-to-batch consistency, the polyclonal reagent recognizes multiple epitopes across the BCAM extracellular region, which can improve signal tolerance for minor antigenic variation between splice isoforms. Researchers commonly pair the antibody with HRP- or fluorophore-conjugated secondary reagents depending on the detection platform. For best stability, refrigerate the vial and dispense into aliquots to limit freeze-thaw cycles, and protect from light when handling fluorophore-labeled secondaries downstream. The reagent is intended for research use only.