Anti-Bax (S163) Antibody

Raised in rabbit and affinity-purified, this polyclonal reagent from Antibodies.com detects the pro-apoptotic Bcl-2 family protein Bax at the region surrounding serine residue 163. Supplied at 1 mg/ml in phosphate buffered saline (pH 7.2) with 0.05% sodium azide as a preservative, the unconjugated antibody is packaged in a 100 µl vial and is validated for western blot and immunofluorescence workflows. Reactivity has been confirmed against human, mouse, and rat samples, supporting comparative apoptosis studies across standard laboratory models. Because the antibody is unconjugated, it can be paired with a secondary reporter of choice for chromogenic, fluorescent, or chemiluminescent readout. The S163 epitope sits within a regulatory stretch of Bax that has been examined in phosphorylation-dependent control of apoptotic signaling, mitochondrial outer membrane permeabilization, and downstream caspase activation, providing a tool for studies of post-translational regulation in programmed cell death.