Anti-Bax Antibody

Raised against the pro-apoptotic Bcl-2 family member that drives mitochondrial outer membrane permeabilization during intrinsic apoptosis, this unconjugated rabbit polyclonal reagent from Antibodies.com targets the 21 kDa Bax protein and cross-reacts with mouse and rat orthologs alongside its primary human reactivity. The 50 µl aliquot is validated for Western blot detection of endogenous Bax levels, immunohistochemistry on formalin-fixed tissue sections, and ELISA-based quantitation workflows, fitting studies of programmed cell death in tumor biology, neurodegeneration, and ischemia-reperfusion injury. Researchers tracking p53-driven apoptosis, cytochrome c release, or shifts in the Bcl-2/Bax ratio can pair this reagent with matched secondary antibodies for both imaging and densitometric readouts. For routine use, keep refrigerated in working aliquots and minimize freeze-thaw cycles to maintain consistent lot-to-lot performance.