Anti-Bax Antibody

This polyclonal antibody targets the Bax protein, a 21 kDa pro-apoptotic member of the Bcl-2 family that drives mitochondrial outer membrane permeabilization and cytochrome c release during programmed cell death. Raised in rabbit, the reagent is supplied as 100 µl of unconjugated antisera validated for western blot, immunohistochemistry, and immunofluorescence workflows on human and rat samples.

Researchers investigating tumor suppression, neurodegeneration, or chemotherapeutic response pathways commonly pair this reagent with anti-Bcl-2 antibodies to monitor shifts in the Bax/Bcl-2 ratio that govern the threshold between cellular survival and caspase activation. Antibodies.com provides the antibody in a single-use vial format with documentation confirming reactivity across both species and the listed applications, supporting studies of intrinsic apoptosis signaling in cultured cell lines and fixed tissue sections.