Anti-Basigin Antibody

This rabbit polyclonal antibody from Antibodies.com targets Basigin (also known as CD147 or EMMPRIN), a heavily glycosylated transmembrane glycoprotein of the immunoglobulin superfamily. Supplied at 100 µg per vial as an unconjugated reagent, it has been validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human samples.

Basigin serves as a chaperone for monocarboxylate transporters MCT1 and MCT4, drives extracellular matrix metalloproteinase (MMP) induction in tumor microenvironments, and acts as a signaling receptor for cyclophilin A. These roles place the protein at the center of cancer invasion and metastasis research, spermatogenesis studies, retinal development investigations, and malaria parasitology, where this reagent supports probing of expression patterns in cell culture and tissue specimens.