Anti-basic beta 2 syntrophin Antibody

Raised in rabbit against the basic beta 2 syntrophin target, this polyclonal reagent from Antibodies.com supports studies of the syntrophin family of dystrophin-associated proteins that anchor signaling components at the cytoplasmic face of the membrane. The unconjugated IgG is supplied as 100 µl of antiserum suitable for western blot, immunohistochemistry, and immunofluorescence workflows on human samples.

Beta-2 syntrophin (SNTB2) functions as an adapter linking the dystrophin complex to a range of intracellular signaling molecules, including ion channels, kinases, and nitric oxide synthase. Detection by this reagent is appropriate for characterizing expression patterns, subcellular distribution at the sarcolemma and other membrane compartments, and for mapping isoform-specific binding partners. Reactivity is reported for human tissue, and the polyclonal format broadens the spectrum of epitopes recognized across denatured and native protein preparations.

Storage recommendations, buffer composition, and recommended working dilutions are detailed on the accompanying product insert. The unconjugated format gives researchers flexibility to pair the antibody with their preferred fluorophore, enzyme reporter, or affinity bead system depending on the downstream assay.