Anti-BAK1 Antibody [Assigned #A10754]

The BCL2 antagonist/killer 1 (BAK1) protein is a central executor of the intrinsic mitochondrial apoptosis pathway, and this unconjugated rabbit monoclonal IgG reagent is engineered to detect it in routine laboratory workflows. Supplied at 100 µL per vial, the antibody supports Western blot, immunoprecipitation, immunofluorescence, and immunohistochemistry applications on human and mouse samples, covering the assay formats most commonly used in apoptosis and oncology research.

BAK1 operates within the BCL-2 family alongside BAX, where it inserts into the outer mitochondrial membrane to drive permeabilization and cytochrome c release during programmed cell death. Investigators studying tumor resistance, chemotherapeutic response, or developmental cell loss use this reagent to monitor endogenous BAK1 levels, confirm expression in engineered cell lines, or pull down BAK1-containing protein complexes.

Distributed by Antibodies.com, the reagent is provided unconjugated and formulated as a rabbit monoclonal of the IgG isotype, allowing flexible pairing with secondary labels of the researcher's choice. Aliquoting upon receipt helps preserve activity across multiple experiments, and refrigerated short-term storage at 4 °C is recommended for working stocks, while long-term freezer storage at -20 °C or below maintains stability for ongoing projects.