Anti-BAK1 Antibody

Produced in rabbit as a polyclonal IgG preparation and reactive against human BCL2 Antagonist/Killer 1 (BAK1), this unconjugated primary antibody from Antibodies.com enables Western Blot and Immunohistochemistry detection of a key pro-apoptotic BCL-2 family protein that drives cytochrome c release through oligomerization in the mitochondrial outer membrane.

Each vial delivers 100 µl of antibody, supporting multiple Western blot membranes or immunohistochemistry runs on paraffin and fixed tissue sections. The polyclonal format offers multi-epitope recognition of BAK1, while the unconjugated chemistry lets researchers pair the reagent with their preferred HRP, biotin, or fluorophore-conjugated secondary antibodies.

Typical research uses include intrinsic apoptosis pathway studies, cancer biology investigations of tumor suppressor mechanisms, mitochondrial outer membrane permeabilization assays, and BCL-2 family signaling crosstalk analyses in human cell lines and tissue samples.