Anti-Bak Antibody

Generated in rabbit and supplied as an unconjugated polyclonal antiserum, this reagent from Antibodies.com targets the pro-apoptotic BCL-2 family member Bak, a protein that resides on the outer mitochondrial membrane and drives cytochrome c release during intrinsic cell death. The antibody is provided at a 100 µl volume and is validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, making it useful for studies of mitochondrial apoptosis in both human and mouse model systems. As a polyclonal reagent, it recognizes multiple epitopes on the Bak protein, which can improve detection of endogenous levels across varied sample types. Researchers investigating DNA damage responses, chemotherapeutic sensitivity, or BCL-2 family signaling can use this reagent to track changes in Bak expression and subcellular localization. The unconjugated format offers flexibility for downstream detection, allowing pairing with species-specific secondary antibodies or custom fluorophore and enzyme conjugates depending on assay design.