Anti-BAIAP2L1 Antibody

BAIAP2L1 (also known as IRTKS, insulin receptor tyrosine kinase substrate of 53 kDa) is an I-BAR domain scaffolding protein central to actin cytoskeleton remodeling, membrane curvature, and cell motility signaling. This polyclonal reagent from Antibodies.com is raised in rabbits against the human BAIAP2L1 target and is supplied as an unconjugated preparation in a 100 µl vial, ready to pair with a secondary antibody of the user's choice for immunofluorescence microscopy or western blot detection.

The antibody is validated for Western blot (WB) and immunofluorescence (IF) applications on human samples. Its polyclonal nature means it recognizes multiple epitopes across the BAIAP2L1 protein, a useful feature when probing isoforms or post-translational modifications. Researchers in podocyte biology, insulin signaling studies, and cancer cell migration research commonly use BAIAP2L1 as a marker of actin-rich protrusions and membrane-remodeling structures.

Because it is unconjugated, the antibody offers flexibility in detection chemistry: it can drive chromogenic western blot development, fluorescent immunostaining, or chemiluminescent readout depending on the chosen secondary. The reagent is shipped refrigerated to maintain activity and should be handled according to standard antibody aliquoting practice to limit freeze-thaw cycles over its working shelf life.