Anti-BAG5 Antibody

BCL2-associated athanogene 5 acts as a nucleotide-exchange co-chaperone for Hsp70 family members and has been investigated most heavily in the context of neurodegenerative disease, where work on Parkinson's models has linked BAG5 activity to modulation of Parkin and to dopaminergic neuron vulnerability. The unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the human BAG5 protein and supplied at 100 µL per vial, ready to dilute into standard western blot and immunofluorescence workflows. Because no reporter label is covalently attached, investigators can pair it with HRP-conjugated anti-rabbit secondaries for chemiluminescent immunoblotting or with fluorophore-conjugated secondaries for indirect IF imaging on fixed cells and tissues. The polyclonal format typically yields a clean band at the expected molecular weight in human cell-line or tissue lysates, supporting studies of proteostasis, mitochondrial stress responses, and BAG-family contributions to apoptosis. Aliquotting on arrival and storage at -20 °C preserves activity across repeated freeze-thaw cycles, while short-term handling at 4 °C suits routine bench sessions. The reagent is for research use only and is validated for human samples, making it a practical option for projects examining chaperone-mediated regulation of protein aggregation and cell survival pathways.