Anti-BAG5 Antibody

BAG5 is a member of the BAG family of co-chaperones that modulate Hsp70/HSC70 chaperone activity and influence apoptosis, cellular stress responses, and proteostasis. This polyclonal antibody from Antibodies.com is raised in rabbit and validated for Western blot detection of endogenous BAG5 protein in lysates from human, rat, and mouse origin.

The reagent ships as a 100 µl volume at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.3. The unconjugated format permits flexible pairing with HRP- or fluorophore-conjugated secondary antibodies in standard immunoblotting workflows.

BAG5 has attracted research interest for its interaction with the E3 ubiquitin ligase parkin and its reported influence on dopaminergic neuron survival, linking the protein to studies of neurodegeneration and mitochondrial homeostasis. Altered BAG5 expression has also been investigated in oncology research, particularly in glioblastoma and other tumor types where the co-chaperone may modulate cell survival pathways.

For research use only. Refrigerate upon receipt to preserve antibody activity and avoid repeated freeze-thaw cycles. Brief centrifugation of the vial prior to use can recover material from the cap.