Anti-BAG3 Antibody

This rabbit polyclonal antibody from Antibodies.com targets human BCL2-associated athanogene 3 (BAG3), a stress-inducible co-chaperone that cooperates with Hsp70 to triage misfolded clients toward selective autophagy and the aggresome pathway. The unconjugated IgG preparation is supplied in a 100 µl volume and is validated for Western blot, where the polyclonal format exposes multiple BAG3 epitopes for stronger signal on endogenous protein in cell lysates and tissue extracts.

BAG3 sits at the intersection of protein quality control, apoptosis regulation, and cytoskeletal dynamics, and altered expression has been documented in cardiomyopathies, neuromuscular disease, and several tumor types including sarcoma and melanoma. The unconjugated format gives researchers freedom to pair the reagent with HRP-conjugated or fluorescent secondary antibodies of their choice and to adjust stringency for chemiluminescent or near-infrared detection platforms. The reagent is raised in rabbit, has a polyclonal clonality with IgG isotype, and reacts with human BAG3.