Anti-BAG1 Antibody

Raised in rabbit against the BAG1 target, this unconjugated polyclonal antibody from Antibodies.com is supplied as 100 µl of reagent at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.5. BAG1 (BCL2-associated athanogene 1) is a multifunctional co-chaperone of Hsp70/Hsc70 that modulates chaperone activity, influences protein refolding, and regulates apoptotic signaling pathways. The reagent is validated for Western Blot (WB) applications and recognizes BAG1 in human and mouse samples, supporting investigations into cancer biology, hormone receptor signaling, and cellular stress responses. BAG1 is expressed as multiple isoforms (BAG-1L, BAG-1M, and BAG-1S) generated by alternative translation initiation, each with distinct subcellular localization patterns and functional consequences. For storage, keep refrigerated and protect from repeated freeze-thaw cycles to maintain antibody integrity. Intended for research use only in studies examining BAG1 expression patterns across diverse tissue types and disease contexts.