Anti-BAF250b Antibody

The BAF250b target, also known as ARID1B, is an ~250 kDa subunit of the SWI/SNF chromatin remodeling complex that repositions nucleosomes to control gene expression. This rabbit polyclonal antibody from Antibodies.com is supplied unconjugated in a 100 µL volume and is validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows. It reacts with human and rat samples, making it useful for cross-species chromatin and transcriptional regulation studies. Investigators apply this reagent to explore ARID1B function in Coffin-Siris syndrome neurodevelopmental research and in cancer biology, where ARID1B loss-of-function mutations are documented across multiple tumor types. The polyclonal design recognizes multiple epitopes across the full-length protein, while the unconjugated format lets researchers pair it with their preferred HRP, fluorophore, or biotinylated secondary detection reagents for flexible assay design.