Anti-BAF250 Antibody

This rabbit polyclonal IgG reagent from Antibodies.com is raised against the BAF250 (ARID1A) subunit of the human SWI/SNF chromatin-remodeling complex. The unconjugated antibody is supplied in a 200 µl vial and is validated for immunofluorescence (IF) on fixed human cells and tissue sections, enabling co-localization analyses with other SWI/SNF components.

ARID1A functions as a tumor suppressor and is among the most frequently mutated chromatin regulators in human cancer. Loss-of-function alterations are common in ovarian clear cell carcinoma, endometrioid carcinoma, and gastric cancers, so this antibody is used by researchers to characterize chromatin remodeling, transcription regulation, and ARID1A status in disease models.

Provided as a polyclonal IgG in liquid format, the reagent is intended for research use only and supports investigations into SWI/SNF-dependent gene regulation, DNA damage responses, and the role of ARID1A in gynecologic and other solid tumor contexts.