Anti-Bad (phospho S155) Antibody

Phosphorylation of Bcl-2-associated death promoter (Bad) at serine 155 is a critical regulatory event controlled primarily by Akt/PKB signaling, where it creates a 14-3-3 binding site that sequesters Bad in the cytoplasm and suppresses its pro-apoptotic activity. This rabbit polyclonal antibody from Antibodies.com selectively recognizes Bad when phosphorylated at S155, making it a reliable readout for Akt pathway activation in studies of cell death, survival signaling, and oncogenic transformation.

Raised in rabbit and purified as a polyclonal IgG preparation, this unconjugated reagent is validated for Western blot detection of endogenous human Bad phosphorylated at Ser155. The antibody is supplied as a 50 µl aliquot and is intended for research use in apoptosis and signal transduction studies, including investigations of PI3K/Akt pathway activity, growth factor survival signaling, and phosphorylation-dependent regulation of the Bcl-2 family.