Anti-BAD Antibody

This polyclonal antibody targets BAD (BCL2-associated agonist of cell death), a BH3-only pro-apoptotic member of the Bcl-2 protein family that governs mitochondrial outer membrane permeabilization and intrinsic apoptotic signaling. Raised in rabbit hosts and supplied by Antibodies.com as an unconjugated reagent, this primary antibody is validated for Western blot and immunohistochemistry applications across human, mouse, and rat sample types. Each vial contains 100 µl of antibody, sufficient for multiple immunoblotting and tissue-staining experiments. BAD functions by heterodimerizing with anti-apoptotic family members such as Bcl-XL and Bcl-2, and its pro-apoptotic activity is suppressed through phosphorylation at key regulatory residues by kinases including AKT, ERK, and PKA. The reagent is therefore widely used by researchers investigating apoptosis regulation, growth factor-dependent cell survival, mitochondrial signaling, and oncogenesis-related pathways.