Anti-BAD (Ab-112) Antibody

The BAD protein, also known as Bcl-2-associated death promoter, is a pro-apoptotic member of the Bcl-2 family that regulates the mitochondrial intrinsic apoptosis pathway. This polyclonal antibody from Antibodies.com is raised in rabbit and specifically recognizes the BAD target at the Ab-112 epitope, a regulatory phosphorylation site whose modification by upstream kinases such as Akt, PKA, and p70 S6 kinase suppresses the pro-apoptotic function of BAD and promotes cell survival.

Supplied as 100 µl of unconjugated polyclonal antiserum, the reagent is validated for western blot (WB) and immunohistochemistry (IHC) workflows against human samples. Store at -20 °C in small aliquots to avoid repeated freeze-thaw cycles. Researchers studying programmed cell death, mitochondrial outer membrane permeabilization, and phosphorylation-dependent regulation in cancer biology, neurodegeneration, and signal transduction will find this reagent useful for detecting endogenous BAD levels and assessing pathway activity in cell lysates and tissue sections.