Anti-b-Catenin (Ab-33) Antibody

Raised in rabbit as a polyclonal reagent, this unconjugated primary antibody recognizes b-Catenin, a multifunctional protein that participates in canonical Wnt signaling and links E-cadherin to the actin cytoskeleton at adherens junctions. The antibody is validated for western blot, immunohistochemistry, and immunofluorescence workflows, and it cross-reacts with human, mouse, and rat samples, supporting comparative studies across model systems and patient-derived tissue. Each vial is supplied as 100 µL of unconjugated antiserum, suitable for direct labeling or secondary detection depending on the assay design. For best stability, aliquot upon arrival and store at -20 °C, avoiding repeated freeze-thaw cycles. Researchers commonly use this reagent to map b-Catenin distribution in epithelial tissues, follow Wnt-driven changes in stem-cell and cancer models, and probe adhesion complex integrity in cultured cell lines. The reagent is offered by Antibodies.com as part of their Primary Antibodies portfolio, intended for research use only.