Anti-AZI1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets AZI1, a centrosomal and basal body protein implicated in primary cilium assembly and centriole cohesion. The unconjugated reagent is supplied at 100 µl and is validated for western blot (WB) and immunohistochemistry (IHC) workflows in human and mouse samples. Researchers studying ciliogenesis, centrosome duplication, or centrosome-related signaling pathways can use this antibody to probe AZI1 expression across tissue lysates and fixed tissue sections. AZI1 (also referenced as CEP131) localizes to mature centrioles and basal bodies, making its detection useful for investigating conditions associated with defective cilia, including ciliopathies, neural tube patterning, and Hedgehog-pathway-linked developmental processes. As a polyclonal reagent raised in rabbit, it offers broader epitope coverage than monoclonal alternatives, which can help when AZI1 abundance is low or when post-translational modification may mask individual epitopes. Storage at 4 °C is recommended for short-term use; aliquots can be stored frozen at -20 °C to limit freeze-thaw cycles and preserve binding activity over the shelf life of the reagent. This antibody is intended for research use only and is not validated for diagnostic or therapeutic applications.