Anti-AXL (phospho-Y703) Antibody

Raised in rabbit against the activation-loop phosphosite Y703 of the AXL receptor tyrosine kinase, this polyclonal phospho-specific reagent from Antibodies.com is supplied as 100 µl of a 1 mg/ml stock in PBS with 0.1% sodium azide and 50% glycerol. It is unconjugated and validated for Western blot detection of phosphorylated AXL in human, mouse, and rat samples, supporting studies of Gas6-driven AXL signaling in oncology, immune regulation, and cell migration research.

Phosphorylation at tyrosine 703 occurs within the AXL kinase domain and serves as a marker of receptor activation following ligand binding. The antibody preferentially recognizes the phosphorylated form, allowing researchers to monitor pathway activity rather than total AXL protein levels. For Western blot work, denaturing lysis conditions supplemented with phosphatase inhibitors are recommended, and the vial should be aliquoted to limit repeated freeze-thaw cycles. Store at -20°C, protect from light, and avoid prolonged exposure to room temperature. Research use only.