Anti-ATXN3 Antibody

rabbit polyclonal reagent from Antibodies.com is raised against ataxin-3 (ATXN3) and is supplied as a 50 µL aliquot at a working concentration of 1.0 mg/mL. The antibody was generated using a recombinant human ATXN3 immunogen and purified by affinity chromatography, and it specifically detects the endogenous total pool of the ATXN3 protein. It is unconjugated and is provided in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol; long-term storage should be at -20 °C with repeated freeze-thaw cycles avoided. Validated applications include Western blotting (WB), immunohistochemistry (IHC) and immunocytochemistry/immunofluorescence (ICC/IF), and the reagent has been confirmed to react with human, mouse and rat samples, making it suitable for cross-species studies of Machado-Joseph disease (MJD/SCA3) and related ataxin-3 biology. As a polyclonal, host-rabbit antibody it is intended for research use only and is not validated for diagnostic or therapeutic applications.