Anti-ATP6V0A2 Antibody

ATP6V0A2 encodes the a2 subunit of the vacuolar-type H+-ATPase (V-ATPase), a multi-subunit proton pump that acidifies intracellular compartments including the Golgi apparatus, endosomes, and lysosomes. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against ATP6V0A2 and validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) applications on human samples. The reagent is supplied as 100 µl of polyclonal antibody in a vial and is intended for research use only, supporting studies of vesicular trafficking, glycosylation disorders, and connective tissue phenotypes linked to ATP6V0A2 dysfunction such as autosomal recessive cutis laxa type IIA (ARCL2A) and wrinkly skin syndrome. Researchers investigating Golgi pH regulation, procollagen processing, and V-ATPase assembly can use this reagent to probe endogenous ATP6V0A2 expression in cultured cells and tissue sections.