Anti-ATP6V0A2 Antibody

The ATP6V0A2 protein is the a2 subunit of the vacuolar-type H+-ATPase (V-ATPase) V0 domain, an integral membrane component that pumps protons across organelle membranes. This Rabbit polyclonal antibody from Antibodies.com targets ATP6V0A2 for Western blot detection in human and mouse samples, supporting research into Golgi acidification, glycosylation pathways, and vesicular trafficking. Supplied as 100 µl at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.10, the unconjugated reagent fits standard immunoblotting protocols across denatured lysate preparations. The polyclonal format in a Rabbit host offers multi-epitope recognition for consistent band detection. ATP6V0A2 mutations are linked to autosomal recessive cutis laxa type IIA (ARCL2A) and wrinkly skin syndrome, so laboratories investigating connective tissue disorders, secretory pathway pH homeostasis, and related cell biology topics will find this reagent a relevant tool. The PBS formulation with sodium azide supports refrigerated storage; aliquoting helps limit freeze-thaw cycles during multi-month use.