Anti-ATP-citrate synthase Antibody

This rabbit polyclonal antibody from Antibodies.com targets ATP-citrate synthase (ACLY), a cytosolic homotetrameric enzyme that catalyzes the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate.

Supplied as 100 µl of unconjugated antiserum, the reagent is validated for western blot, immunofluorescence, and ELISA applications. The polyclonal format enables recognition of multiple epitopes on the full-length ~120 kDa subunit, supporting consistent detection in both denaturing and native sample preparations.

Reactivity has been confirmed against human, mouse, rat, and monkey samples, making it useful across rodent and primate research models. ACLY sits at a metabolic branch point feeding de novo lipogenesis and cholesterol biosynthesis, and altered expression has been linked to cancer cell metabolism and metabolic disorders.