Anti-Atm Antibody

Raised in rabbit as a polyclonal reagent, this unconjugated antibody targets the Atm (Ataxia-telangiectasia mutated) serine/threonine kinase and is supplied by Antibodies.com as 100 µl of ready-to-use stock. Atm sits at the head of the DNA double-strand break response, phosphorylating p53, Chk2, BRCA1, and H2AX to coordinate cell cycle arrest, apoptosis, and homologous recombination repair, so the reagent is commonly selected for cancer biology, radiosensitivity, and genomic stability studies. Validated workflows include Western blot, immunohistochemistry, and ELISA, with confirmed reactivity against human and mouse samples — useful when comparing patient-derived lines with knockout mouse models. The unconjugated format leaves the choice of label open, allowing secondary detection with HRP, fluorophore, or biotin conjugates depending on the assay, and the polyclonal pool increases the chance of recognizing multiple epitopes on the large 350 kDa Atm protein.