Anti-ATM (Ab-1981) Antibody

Produced in rabbit as a polyclonal reagent, this unconjugated primary antibody from Antibodies.com targets ATM kinase at the phosphorylated Ser1981 site, a hallmark modification that occurs within minutes of double-strand DNA break induction. The 100 µl format supports both western blot and immunofluorescence applications on human cells and tissue sections, allowing researchers to track activation of the ATM-driven DNA damage response, including downstream phosphorylation of p53 and Chk2 and the formation of γH2AX nuclear foci. Polyclonal epitope coverage strengthens signal detection in whole-cell lysates and fixed-cell preparations. Each vial is aliquoted for single-use convenience and should be stored refrigerated with appropriate handling to preserve phospho-specific binding activity through repeated experimental cycles.