Anti-ATIC Antibody

Raised in rabbit and purified by antigen-affinity chromatography, this polyclonal reagent from Antibodies.com targets the bifunctional purine biosynthesis protein ATIC (also known as AICAR transformylase/IMP cyclohydrolase or PURH). It is supplied as an unconjugated IgG at 1.0 mg/mL in a 50 µL aliquot, formulated in phosphate-buffered saline (pH 7.4) with 150 mM NaCl, 0.02% sodium azide, and 50% glycerol. The antibody detects the endogenous total ATIC protein and is validated for Western blotting, immunohistochemistry, and immunofluorescence (ICC/IF) applications, with cross-reactivity confirmed against human, mouse, and rat samples. For handling, the vial is shipped at 4 °C and should be aliquoted upon arrival and stored at –20 °C, avoiding repeated freeze/thaw cycles. The immunogen is a recombinant human ATIC protein, ensuring specificity for the native target. Intended for research use only, this Antibodies.com reagent (catalog A35569, 50 µL size) provides a reliable tool for laboratories studying de novo purine biosynthesis and related metabolic pathways across multiple model systems.