Anti-ATIC Antibody

This mouse monoclonal reagent from Antibodies.com targets ATIC, a bifunctional enzyme that catalyzes the final two steps of de novo purine biosynthesis. ATIC is widely studied in cancer metabolism and antifolate drug response research, where altered expression is linked to cell proliferation and tumor progression.

Validated for Western Blot applications, this unconjugated antibody cross-reacts with human, mouse, and rat samples, supporting comparative studies across mammalian model systems. The unconjugated format allows flexible secondary antibody selection for chemiluminescent or fluorescent detection.

Supplied as 100 µl of purified protein in a buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% sodium azide, and 50% glycerol, the reagent is provided ready to use in standard immunoblotting workflows. Store refrigerated and protect from light; the glycerol cryoprotectant helps preserve antibody activity through repeated freeze-thaw cycles.