Anti-ATG4C Antibody

Raised in rabbit against a recombinant full-length human ATG4C immunogen, this affinity-purified polyclonal IgG reagent from Antibodies.com is supplied as a 50 µl aliquot at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, with purity exceeding 95% by SDS-PAGE. The unconjugated antibody is validated for Western blot (WB) and immunohistochemistry (IHC) workflows and detects endogenous levels of the ~53 kDa ATG4C cysteine protease in human, mouse, and rat samples. ATG4C is the autophagy-related4C cysteine peptidase responsible for cleaving the C-terminal region of MAP1LC3, GABARAPL2, and GABARAP, liberating form I and producing the smaller form II that exposes a C-terminal glycine for phosphatidylethanolamine conjugation and autophagosome binding. For short-term use the vial should be kept at 4 °C, while longer-term storage is recommended at –20 °C in aliquots to avoid repeated freeze-thaw cycles. The product ships from China with insulated cold-pack packaging to protect stability in transit, and is intended strictly for research use, not for diagnostic or therapeutic applications.