Anti-ATF4 (phospho S245) Antibody

This rabbit polyclonal IgG antibody from Antibodies.com is raised against Activating Transcription Factor 4 (ATF4) phosphorylated at serine 245, a post-translational modification linked to the integrated stress response and eIF2α signaling. Supplied as 100 µl of unconjugated antiserum, the reagent is validated for Western blot and immunohistochemistry on human samples and is applicable to studies of amino acid deprivation, oxidative stress, and ER stress pathways in which ATF4 acts as a master transcriptional regulator. The polyclonal format increases the likelihood of detecting the target across multiple epitope exposures following S245 phosphorylation, while the unconjugated IgG presentation allows researchers to pair the antibody with their preferred secondary detection reagent and labeling strategy.