Anti-ATF3 Antibody

The Antibodies.com polyclonal reagent recognizes Activating Transcription Factor 3 (ATF3), a member of the ATF/CREB family of stress-responsive transcription factors. ATF3 is rapidly induced by a variety of cellular insults including DNA damage, oxidative stress, and endoplasmic reticulum stress, positioning it as a key readout for stress-signaling research.

This unconjugated rabbit polyclonal antibody is validated for western blot and immunohistochemistry workflows and detects endogenous ATF3 in human, mouse, and rat samples. The 100 µL vial of liquid antibody is supplied ready for use in standard immunoblotting and chromogenic tissue-staining protocols.

Common applications include mapping of neuronal injury responses, where ATF3 expression serves as a marker for damaged or stressed neurons, as well as cancer biology investigations into tumor suppression pathways and stress-induced apoptosis. For best results, aliquot the antibody upon arrival, store refrigerated, and protect from light; repeated freeze-thaw cycles should be avoided to preserve binding activity.