Anti-ATF2 (V63) Antibody

Activating transcription factor 2 (ATF2) is a basic leucine zipper protein in the ATF/CREB family that binds the cAMP response element and mediates transcriptional responses to cellular stress and DNA damage. The rabbit polyclonal antibody offered by Antibodies.com enables detection of this regulator across standard immunodetection workflows.

Supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, the reagent is unconjugated and presented in a 100 µl vial format. This primary antibody is validated for Western blot (WB), immunohistochemistry (IHC), and immunoprecipitation (IP), supporting diverse experimental approaches from cell lysate analysis to tissue localization studies.

Cross-reactivity extends to Human, Mouse, and Rat samples, giving researchers flexibility across commonly used model systems and human-derived specimens. The polyclonal host profile allows recognition of multiple epitopes on ATF2, which can be useful when working with protein variants or partial degradation products.

For storage, aliquot the antibody and store at -20°C; protect from light and limit freeze-thaw cycles to preserve binding activity. The product is intended for research use only and supports investigations of stress-activated kinase signaling, including phosphorylation-dependent regulation of ATF2 in DNA damage response pathways.