Anti-ATF-5 Antibody

This rabbit polyclonal reagent from Antibodies.com targets ATF5, a basic leucine zipper transcription factor of the ATF/CREB family that governs cellular stress responses, differentiation programs, and survival signaling. The unconjugated antibody is supplied as 100 µl of liquid formulation and is validated for Western blot detection of endogenous ATF5 protein, immunohistochemical localization in formalin-fixed tissue sections, and ELISA-based quantitative work.

The antibody has been tested for cross-reactivity with human, mouse, and rat samples, supporting studies of ATF5 in glioblastoma and other neural-derived tumor models, hypoxia and oxidative stress responses, and lineage specification in neural progenitor populations. Because ATF5 expression is elevated in several cancer types and modulated by unfolded protein response signaling, the reagent is useful for investigating tumor biology and stress-adaptation mechanisms.

Researchers commonly apply it at empirically determined dilutions for immunoblotting of whole-cell lysates, chromogenic IHC on paraffin sections, and standard ELISA protocols. Storage recommendations and lot-specific validation data are provided with the shipment, allowing confident integration into multi-antibody panels exploring transcription factor networks.