Anti-ATF-3 Antibody

This rabbit polyclonal antibody targets Activating Transcription Factor 3 (ATF-3), a stress-responsive member of the ATF/CREB bZIP transcription factor family that is rapidly induced by diverse cellular insults including DNA damage, oxidative stress, and inflammatory signals. Produced by Antibodies.com as an unconjugated, affinity-purified reagent, it is supplied in a 100 µl vial and is validated for Western blot, immunohistochemistry, and ELISA workflows across human, mouse, and rat sample types. The polyclonal format offers broader epitope coverage than monoclonal alternatives, which is particularly useful when probing endogenous ATF-3 isoforms that may be regulated in tissue-specific or stimulus-dependent contexts. Researchers studying stress granule formation, neuronal injury responses, tumor suppressor pathways, or immune cell activation commonly rely on this reagent to track both basal and induced ATF-3 expression in cell lysates and fixed tissue sections. The unconjugated presentation allows flexible pairing with user-selected secondary reagents and custom detection strategies, including chromogenic IHC, immunofluorescence, or HRP-based Western blot detection.