Anti-ATF-1 Antibody

The ATF-1 polyclonal reagent from Antibodies.com is a rabbit-derived primary antibody raised against the activating transcription factor 1 protein. Supplied as a 100 µl aliquot in unconjugated format, this polyclonal antibody supports WB, IHC, and ELISA workflows investigating cAMP-responsive transcription signaling. The antibody recognizes the ATF1 target in human and mouse samples, making it a useful reagent for comparative studies across species in cell signaling, gene regulation, and CREB-pathway research.

ATF-1 is a member of the CREB/ATF family that binds to cAMP response elements (CRE) in promoter regions and modulates transcription of downstream genes involved in stress response, cell growth, and differentiation. Researchers commonly use this reagent to examine phosphorylation events, CRE-dependent transcriptional activity, and tissue-specific expression patterns in research use only applications.

Aliquoting upon first use is recommended to limit freeze-thaw cycles, and the unconjugated format allows flexibility with secondary antibody selection and custom detection chemistries such as HRP, biotin, or fluorophore conjugates. Each vial supports multiple experimental setups depending on dilution ratios.