Anti-Ataxin 3 Antibody

Raised in rabbit, this unconjugated polyclonal primary antibody targets Ataxin 3 (ATXN3), a deubiquitinating enzyme whose polyglutamine-expanded form drives spinocerebellar ataxia type 3, also known as Machado-Joseph disease. Distributed by Antibodies.com in a 100 µl volume, the reagent is validated for Western Blot and Immunohistochemistry on human samples, supporting studies of neuronal inclusions, proteostasis, and polyglutamine toxicity in neurodegenerative disease models. The polyclonal format enables recognition of multiple epitopes across the ATXN3 sequence, aiding detection of full-length protein as well as cleavage fragments in cell lysates and in fixed neural tissue sections.