Anti-ATAD2 Antibody

ATAD2 is an ATP-dependent chromatin remodeler and bromodomain-containing transcriptional co-activator implicated in several human cancers. It interacts with acetylated histones and core transcription factors to drive expression of proliferation-linked genes, and elevated ATAD2 levels have been documented in breast, lung, ovarian, colorectal, and prostate tumor tissue relative to matched normal controls. The protein's bromodomain and AAA+ ATPase domains make it a focus of cancer biology research, particularly around cell cycle progression and hormone receptor signaling.

This Rabbit polyclonal IgG reagent from Antibodies.com is raised against human ATAD2 and supplied as an unconjugated antiserum at 100 µL per vial, ready for Western Blot workflows on human cell or tissue lysates. As an unconjugated reagent in the IgG class, it allows downstream detection chemistries to be chosen by the end user, including HRP- or fluorophore-conjugated secondaries and standard ECL or fluorescence imaging readouts.

For handling, aliquot upon first thaw to limit freeze-thaw cycles and store at -20 °C in a manual defrost freezer; short-term storage at 4 °C is acceptable for active vials. Protect from light when working with the liquid. Because the antibody is polyclonal, it recognizes multiple epitopes across the ATAD2 sequence, supporting detection of denatured targets following SDS-PAGE and Western transfer, and reactivity against human antigen has been verified. This product is intended for research use only.