Anti-ASPSCR1 Antibody

ASPSCR1 (also called ASPL, UBXD9, or TUG) is a UBX-domain-containing protein linked to intracellular trafficking of glucose transporters and to the t(X;17)(p11;q25) translocation that generates the ASPSCR1-TFE3 fusion characteristic of alveolar soft part sarcoma. This rabbit polyclonal reagent from Antibodies.com is raised against the human ASPSCR1 protein and detects both the endogenous full-length target and fusion contexts commonly investigated in sarcoma research.

The antibody is supplied as a polyclonal IgG fraction at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a stabilizer, shipped in a 100 µl vial that can be aliquoted for repeated use while minimizing freeze-thaw cycles. Reactivity has been validated on human and mouse samples, supporting translational work in xenograft, syngeneic, and primary tissue studies.

Recommended applications include western blot detection of ASPSCR1 in cell and tumor lysates, and immunohistochemistry on formalin-fixed paraffin-embedded tissue, where nuclear and cytoplasmic staining patterns can be used to screen for ASPSCR1-TFE3 fusion-positive lesions. Store refrigerated at 4 degrees C with the glycerol cryoprotectant; for longer-term storage, keep frozen at -20 degrees C in working aliquots to preserve titer. For research use only, this unconjugated antibody also works as a primary reagent in immunofluorescence, immunoprecipitation, and chromatin workflows beyond its core validated uses.