Anti-Aspergillus Antibody

This rabbit polyclonal antibody from Antibodies.com is raised against Aspergillus antigens and supplied as a purified IgG fraction for immunohistochemistry workflows. The unconjugated format lets laboratories pair the reagent with their preferred HRP or alkaline phosphatase detection system and chromogen when staining formalin-fixed paraffin-embedded tissue sections.

Histopathology and mycology laboratories use the reagent to visualize Aspergillus hyphae and conidial elements within infected tissue, supporting differential diagnosis of invasive aspergillosis, aspergilloma, and other opportunistic fungal infections. Because the polyclonal response targets multiple Aspergillus antigens, staining highlights both germinating conidia and the septate, acute-angle branching hyphae characteristic of tissue-invasive growth, which is useful when fungal burden is low or morphology is equivocal on routine H&E.

Each vial contains 500 µl of antibody, sufficient for numerous IHC runs depending on section thickness, antigen retrieval protocol, and dilution. Laboratories commonly titrate the reagent on positive-control slides containing known Aspergillus-infected lung or sinus tissue, and most protocols recommend a negative tissue control and an isotype control to confirm staining specificity.

Storage guidance includes short-term refrigeration and aliquoting for longer-term freezer storage to preserve activity. Refer to the lot-specific data sheet for recommended dilutions, antigen retrieval conditions, and incubation times before beginning any immunohistochemistry run.