Anti-ASNS Antibody

Produced in rabbit as an unconjugated polyclonal reagent, this Antibodies.com antibody targets asparagine synthetase (ASNS), the glutamine-hydrolyzing enzyme that converts aspartate and glutamine to asparagine and glutamate using ATP. The immunogen-derived IgG fraction is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial suitable for multiple experiments.

Validation data confirm reliable performance in Western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples, supporting research into amino acid biosynthesis, cellular stress responses, and tumor metabolic adaptation. Because ASNS expression is frequently elevated in asparaginase-resistant leukemias and in solid tumors that rely on extracellular asparagine depletion strategies, this reagent is a practical tool for studies of cancer metabolism, leukemia chemotherapy response, and tissue-level expression profiling.

The unconjugated format gives laboratories freedom to conjugate the antibody to their preferred reporter or to use it directly in immunoprecipitation and chromatin-associated pull-down protocols, while the glycerol-stabilized buffer allows convenient storage at standard freezer conditions for repeated use across an extended project.