Anti-ASIC3 Antibody

The ASIC3 polyclonal reagent from Antibodies.com is a rabbit-derived IgG preparation validated for Western blot detection of the acid-sensing ion channel 3 protein in mouse and rat samples. ASIC3 is a proton-gated cation channel predominantly expressed in sensory neurons of the dorsal root ganglia and is widely investigated in nociception, inflammatory pain, and mechanosensation research.

Supplied as 200 µl of unconjugated polyclonal antiserum raised in rabbit, this primary antibody supports immunoblotting of Acid-Sensing Ion Channel 3 (Accn3) in tissue homogenates and cell lysates. Researchers commonly deploy it to probe ASIC3 expression changes in models of nerve injury, chronic pain, and gastrointestinal mechanoreceptor studies. The IgG isotype allows pairing with standard anti-rabbit secondary reagents for chemiluminescent Western blot workflows.

For handling, aliquot the antibody upon arrival to limit freeze-thaw cycles and store refrigerated; this preserves binding activity across multiple experimental uses. Intended for research use only.